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Authors: Sen Pei, Sasikiran Kandula, Jeffrey Shaman* Division of Environmental Well being Sciences, Mailman College of Public Well being, Columbia College Summary Assessing the consequences of early non-pharmaceutical interventions1-5 on COVID-19 unfold in the USA is essential for understanding and planning future management measures to fight the continuing pandemic6-10. Right here we use county-level observations of reported infections and deaths11, at the side of human mobility knowledge12 and a metapopulation transmission mannequin13,14, to quantify adjustments of illness transmission charges in US counties from March 15, 2020 to Could 3, 2020. We discover vital reductions of the essential reproductive numbers in main metropolitan areas
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